Hydrochloric Acid → Hydrochloric Acid

Participants

Reaction Steps

A solution of tert-Butyl 1′-methyl-2′-oxo-1′,2′,3,6-tetrahydro-4,4′-bipyridine-1(2H)-carboxylate (100 mg, 0.3 mmol) in AcOEt (2 mL) was treated with 4 M of hydrogen chloride in 1,4-dioxane (0.1722 mL, 0.6888 mmol). The mixture was stirred at r.t. 2 h., and concentrated under reduced pressure to afford the desired compound as HCl salt which was directly used in the next step reaction without further purification. LCMS (M+H)+: m/z=191.1.

Provenance & Evidence