HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(7-bromo-3-methyl-3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine → HCID 59402261, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(7-bromo-3-methyl-3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine | HCID 59402317 | — |
| Reactant | HCID 68472207 | HCID 68472207 | — |
| Product | HCID 59402261 | HCID 59402261 | — |
Reaction Steps
This compound was prepared by using procedures analogous to those described for the synthesis of Example 2 starting from 4-(7-bromo-3-methyl-3,4-dihydroisoquinolin-2(1H)-yl)-6-(4-methylpiperazin-1-yl)pyrimidin-2-amine and (6-cyano-5-methylpyridin-3-yl)boronic acid (Combi-Blocks, Cat. No. PN-5814). LCMS (M+H)+: m/z=441.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436008B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-edd4fab5a83d403d87cd8d3141000280 |
| Source note | uspto-grants-2013_05 |