1,2-Dimethoxyethane → 2-Amino-4-(3,5-dimethyl-pyridin-2-yl-methoxy)-6-pyridin-2-yl-pyrimidine-5-carbonitrile

HRID 209048Notes

Reaction equation

HRID 209048 reaction equation
[CH2:29]1[CH2:30][CH2:31][C:32]2=[N:37][CH2:36][CH2:35][CH2:34][N:33]2[CH2:38][CH2:39]1.[CH3:19][c:20]1[c:21]([CH2:27][OH:28])[n:22][cH:23][c:24]([CH3:26])[cH:25]1.[CH3:40][O:41][CH2:42][CH2:43][O:44][CH3:45].[NH2:1][c:2]1[n:3][c:4](-[c:13]2[n:14][cH:15][cH:16][cH:17][cH:18]2)[c:5]([C:11]#[N:12])[c:6]([S:8]([CH3:9])=[O:10])[n:7]1>>[NH2:1][c:2]1[n:3][c:4](-[c:13]2[n:14][cH:15][cH:16][cH:17][cH:18]2)[c:5]([C:11]#[N:12])[c:6]([O:28][CH2:27][c:21]2[c:20]([CH3:19])[cH:25][c:24]([CH3:26])[cH:23][n:22]2)[n:7]1

Participants

5

Reactant 4

HCID 80711,2-DimethoxyethaneHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 10630548(3,5-Dimethylpyridin-2-yl)methanolHCID 185076952-Amino-4-methanesulfinyl-6-pyridin-2-yl-pyrimidine-5-carbonitrile

Product 1

HCID 185076632-Amino-4-(3,5-dimethyl-pyridin-2-yl-methoxy)-6-pyridin-2-yl-pyrimidine-5-carbonitrile

Sources & evidence

ORD record
ord-554faae677d14ea0bff548b48059dc0e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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