Hydrochloric Acid → HCID 178478256, compound

Participants

Reaction Steps

To a solution of (S)-tert-butyl 2-(5-(4-(3-(2-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-1H-imidazol-4-yl)phenoxy)phenyl)-1H-imidazol-2-yl)pyrrolidine-1-carboxylate (500 mg, 0.78 mmol) in dichloromethane was added HCl (1 M, 3 mL), the reaction product precipitated after stirring at room temperature. Filtration and drying in the vacuum oven afforded 2-((S)-pyrrolidin-2-yl)-5-(4-(3-(2-((S)-pyrrolidin-2-yl)-1H-imidazol-4-yl)phenoxy)phenyl)-1H-imidazole hydrochloride (220 mg).

Provenance & Evidence