HCID 11033857, compound → Ethyl 3-oxododecanoate

HRID 2090591Notes

Reaction equation

HRID 2090591 reaction equation
[C:1]([CH:12]1C(=O)O[C:15](C)([CH3:19])[O:14][C:13]1=[O:21])(=[O:11])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10]>C(O)C>[O:11]=[C:1]([CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])[CH2:12][C:13]([O:14][CH2:15][CH3:19])=[O:21]

Participants

3

Reactant 1

HCID 11033857HCID 11033857, compound

Product 1

HCID 3017756Ethyl 3-oxododecanoateYield 98%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The resulting 5-decanoyl-2,2-dimethyl-1,3-dioxane-4,6-dione was allowed to reflux in ethanol for 2 hours, and then concentrated under reduced pressure. The resulting residue was purified using silica gel chromatography (developing solvent: n-hexane/ethyl acetate=3/7) to obtain the ethyl 3-oxododecanoate shown by the formula below.

Workup

  1. concentrationconcentrated under reduced pressure
  2. customThe resulting residue was purified

Sources & evidence

ORD record
ord-7c9fd7c3503b41568ac8030551dd972c
Source dataset
uspto-grants-2013_05
Patent number
US08436210B2

Reaction notes

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