HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Fluoro-2-methylphenyl)boronic acid → methyl 1-(4-fluoro-2-methylphenyl)-3-methyl-1H-pyrazole-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Fluoro-2-methylphenyl)boronic acid | HCID 2734665 | — |
| Reactant | HCID 178498883 | HCID 178498883 | — |
| Product | methyl 1-(4-fluoro-2-methylphenyl)-3-methyl-1H-pyrazole-4-carboxylate | HCID 66777491 | 68% |
Reaction Steps
Using methyl 3-methyl-1H-pyrazole-4-carboxylate (6.25 g) synthesized in Example 1(3) and 4-fluoro-2-methylphenylboronic acid (13.9 g) and in the same manner as in Example 17(1), the title object compound (7.5 g, 68%) was obtained as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436043B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-385acdb7d6dd4afab7b80362171e31f3 |
| Source note | uspto-grants-2013_05 |