HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dichloro-5-(trifluoromethyl)pyridine → methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-3-methyl-1H-pyrazole-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dichloro-5-(trifluoromethyl)pyridine | HCID 112234 | — |
| Reactant | HCID 178498883 | HCID 178498883 | — |
| Product | methyl 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-3-methyl-1H-pyrazole-4-carboxylate | HCID 66778425 | 81.5% |
Reaction Steps
Using methyl 3-methyl-1H-pyrazole-4-carboxylate (3.8 g) synthesized in Example 1(3) and 2,3-dichloro-5-trifluoromethylpyridine (5.8 g) and in the same manner as in Example 1(4), the title object compound (7.0 g, 78%) was obtained as a pale-yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08436043B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-dbe52f27ff264020ad2e152b123fe3bc |
| Source note | uspto-grants-2013_05 |