Dimethylformamide dimethyl acetal → HCID 66778583, compound

HRID 2090899Notes

Reaction equation

HRID 2090899 reaction equation
O=[C:2]([CH2:8][CH3:9])[CH2:3][C:4]([O:6][CH3:7])=[O:5].[CH3:10]OC(OC)N(C)C.O.[CH3:19][O:20][C:21]1[CH:26]=[CH:25][C:24]([NH:27][NH2:28])=[CH:23][CH:22]=1>>[CH2:8]([C:2]1[C:3]([C:4]([O:6][CH3:7])=[O:5])=[CH:10][N:27]([C:24]2[CH:25]=[CH:26][C:21]([O:20][CH3:19])=[CH:22][CH:23]=2)[N:28]=1)[CH3:9]

Participants

4

Reactant 3

HCID 78373Dimethylformamide dimethyl acetalHCID 121699Methyl 3-oxovalerateHCID 66778904HCID 66778904, compound

Product 1

HCID 66778583HCID 66778583, compoundYield 84%

Procedure

Using methyl 3-oxopentanoate (3.3 g), dimethylformamide dimethylacetal (3.6 mL) and p-methoxyphenylhydrazine monohydrate (4.7 g) and in the same manner as in Example 15(1), the title object compound (6.0 g, 84%) was obtained as an oil.

Sources & evidence

ORD record
ord-a6e36ba69e2d4c7bad0548eef6f927c3
Source dataset
uspto-grants-2013_05
Patent number
US08436043B2

Reaction notes

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