Dimethylformamide dimethyl acetal → HCID 66777394, compound

HRID 2090904Notes

Reaction equation

HRID 2090904 reaction equation
[CH3:1][CH:2]([CH3:10])[C:3](=O)[CH2:4][C:5]([O:7][CH3:8])=[O:6].[CH3:11]OC(OC)N(C)C.Cl.[CH3:20][O:21][C:22]1[CH:27]=[CH:26][C:25]([NH:28][NH2:29])=[CH:24][CH:23]=1>>[CH3:20][O:21][C:22]1[CH:27]=[CH:26][C:25]([N:28]2[CH:11]=[C:4]([C:5]([O:7][CH3:8])=[O:6])[C:3]([CH:2]([CH3:10])[CH3:1])=[N:29]2)=[CH:24][CH:23]=1

Participants

4

Reactant 3

HCID 78373Dimethylformamide dimethyl acetalHCID 27239044-Methoxyphenylhydrazine hydrochlorideHCID 2759969Methyl 4-methyl-3-oxopentanoate

Product 1

HCID 66777394HCID 66777394, compoundYield 51%

Procedure

Using methyl 4-methyl-3-oxopentanoate (3.6 g), dimethylformamide dimethylacetal (3.5 mL) and p-methoxyphenylhydrazine monohydrochloride (4.5 g) and in the same manner as in Example 15(1), the title object compound (3.5 g, 51%) was obtained as a pale-yellow solid.

Sources & evidence

ORD record
ord-33fda426d0634bafaf58cb06a5dec390
Source dataset
uspto-grants-2013_05
Patent number
US08436043B2

Reaction notes

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