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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 209109Generated: October 27, 2026

Bicarbonate Ion → 1-(2,2-Difluoroethyl)-4-[2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazine

https://huagongshe.com/reaction/209109

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBicarbonate IonHCID 769—
ReactantPotassium CationHCID 813—
ReactantSodium ionHCID 923—
ReactantDiethyl EtherHCID 3283—
ReactantDimethylformamideHCID 6228—
ReactantCarbonate IonHCID 19660—
ReactantIodide IonHCID 30165—
Reactant2-Bromo-1,1-difluoroethaneHCID 136186—
Reactant1-[2-(3,3,5,5-Tetramethylcyclohexyl)phenyl]piperazineHCID 11992284—
Product1-(2,2-Difluoroethyl)-4-[2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazineHCID 23141703—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-36c9361fe03343e6888c34f4087f398c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)