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HRID2091897

反应详情

EQUATION

反应方程式

HRID 2091897 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)OB(c2c(F)ccc3c2ccn3[Si](C)(C)C(C)(C)C)OC1(C)C
HCID57506725

未命名化合物

结构：CC1(C)CCN(Cc2ccc3nc(Cl)nc(N4CCOCC4)c3n2)C1
HCID58404995

未命名化合物

PRODUCTS

生成物

1
结构：CC1(C)CCN(Cc2ccc3nc(-c4c(F)ccc5[nH]ccc45)nc(N4CCOCC4)c3n2)C1
HCID53378794

未命名化合物

PROCEDURE

实验过程

4-(2-chloro-6-((3,3-dimethylpyrrolidin-1-yl)methyl)pyrido[3,2-d]pyrimidin-4-yl)morpholine (0.28 g) was reacted with 1-(tert-butyldimethylsilyl)-5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole via General Procedure A to produce 70.2 mg of 144 following reverse phase HPLC purification. MS (Q1) 461.2 (M)+

WORKUP

后处理

  1. customto produce
  2. custom70.2 mg of 144 following reverse phase HPLC purification