Sodium Carbonate → HCID 59586806, compound

Participants

Reaction Steps

The mixture isoxazol-3-amine (36 μL, 0.50 mmol), 2,4,5-trichloropyrimidine (57 μL, 0.5 mmol), and sodium carbonate (53 mg, 0.5 mmol) in 3 mL of EtOH is heated at 60° C. for 48 hrs. The precipitate is filtered, washed by cold EtOH, and dried in vacuo to afford N-(2,5-Dichloropyrimidin-4-yl)isoxazol-3-amine; ESMS m/z 231.0 (M+H+).

Provenance & Evidence