Trifluoroacetic acid → HCID 68431410, compound

Participants

Reaction Steps

tert-Butyl 2-(2-{5-bromo-6-oxo-4-[(1R,2R,3R,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-3-ylamino]pyridazin-1(6H)-yl}acetamido)acetate (18 mg, 0.036 mmol) prepared in Synthetic Example 10 in dichloromethane (1 mL) was stirred with trifluoroacetic acid (0.1 mL) at room temperature. After completion of the reaction, the reaction solution was concentrated to give the desired product (15 mg, 94% yield).

Provenance & Evidence