HCID 68429305, compound → HCID 68432017, compound

Participants

Reaction Steps

4-Bromo-5-[(1R,2R,3R,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-3-ylamino]pyridazin-3(2H)-one (300 mg, 0.92 mmol) and 10% palladium-carbon (50 wt %, 30 mg) in methanol were stirred in a hydrogen stream at room temperature for 1 day. The reaction solution was filtered through celite, and the filtrate was concentrated to give the desired product (100% yield).

Provenance & Evidence