Hydrochloric Acid → HCID 59574187, compound

HRID 2092089Notes

Reaction equation

HRID 2092089 reaction equation
[NH:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=[O:8])=[CH:5][CH:4]=1)[NH2:2].[C:12](O)(=O)/[C:13](=[C:15](\[CH:17]=[O:18])/[Br:16])/[Br:14].Cl>C(O)C.O>[Br:14][C:13]1[CH:12]=[N:2][N:1]([C:3]2[CH:4]=[CH:5][C:6]([C:7]([OH:9])=[O:8])=[CH:10][CH:11]=2)[C:17](=[O:18])[C:15]=1[Br:16]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 120894-Hydrazinobenzoic acidHCID 3033972Mucobromic Acid

Product 1

HCID 59574187HCID 59574187, compoundYield 93.1%

Reagents, catalysts & solvents 1

HCID 19096565Water ethanolSolvent

Procedure

4-Hydrazinobenzoic acid (2.00 g, 13.1 mmol) in ethanol-water (1:1, 20 mL) was stirred with mucobromic acid (2.26 g, 8.76 mmol) and concentrated hydrochloric acid (10 mL) at 70° C. for 2 days. After cooling, the resulting crystals were collected by filtration, washed with ethanol and water and dried under reduced pressure to give the desired product (3.05 g, 62% yield).

Workup

  1. temperatureAfter cooling
  2. filtrationthe resulting crystals were collected by filtration
  3. washwashed with ethanol and water
  4. customdried under reduced pressure

Sources & evidence

ORD record
ord-f1ccb81a4b554016b70444325e752a8b
Source dataset
uspto-grants-2013_05
Patent number
US08440666B2

Reaction notes

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