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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2092189Generated: November 3, 2026

Hydrochloric Acid → HCID 25154342, compound

https://huagongshe.com/reaction/2092189

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 44474551HCID 44474551—
SolventDichloromethaneHCID 6344—
ProductHCID 25154342HCID 25154342—

Reaction Conditions

Temperature50 °C

Reaction Steps

A solution of tert-butyl 5-(3-(phenylsulfonyl)quinolin-8-yl)hexahydropyrrolo[2,3-c]pyrrole-1(2H)-carboxylate (92 mg, 0.19 mmol) in CH2Cl2 (5 ml) was treated with hydrochloric acid (4M in dioxane, 2 ml) at 0° C. and then stirred at 50° C. for 16 h. After concentration, the product was washed with EtOAc and dried in vacuo to give the title compound (80 mg, 100% as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08440694B2
Source datasetuspto-grants-2013_05
ORD IDord-cd215cd387f24de4966cd963410d407f
Source noteuspto-grants-2013_05