Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 44474551 | HCID 44474551 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 25154342 | HCID 25154342 | — |
Reaction Steps
A solution of tert-butyl 5-(3-(phenylsulfonyl)quinolin-8-yl)hexahydropyrrolo[2,3-c]pyrrole-1(2H)-carboxylate (92 mg, 0.19 mmol) in CH2Cl2 (5 ml) was treated with hydrochloric acid (4M in dioxane, 2 ml) at 0° C. and then stirred at 50° C. for 16 h. After concentration, the product was washed with EtOAc and dried in vacuo to give the title compound (80 mg, 100% as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08440694B2 |
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| Source dataset | uspto-grants-2013_05 |
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| ORD ID | ord-cd215cd387f24de4966cd963410d407f |
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| Source note | uspto-grants-2013_05 |
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