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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2092205Generated: October 31, 2026

Hydrochloric Acid → HCID 68728360, compound

https://huagongshe.com/reaction/2092205

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant3-(3-Fluorophenylsulfonyl)-8-iodoquinolineHCID 67314157—
ReactantHCID 68725523HCID 68725523—
ProductHCID 68728360HCID 68728360—

Reaction Steps

0.088 g of 5-(3-(3-fluorophenylsulfonyl)quinolin-8-yl)octahydropyrrolo[3,4-b]pyrrol-1-ium chloride were prepared by analogy to the methods of Examples 27 and 28 by coupling of 3-(3-fluorophenylsulfonyl)-8-iodoquinoline with 1-(tert-butoxycarbonyl)-octahydropyrrolo[2,3-c]pyrrol-5-ium chloride and subsequent deprotection of the tert-butyl-oxycarbonyl derivative with HCl in isoproanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08440694B2
Source datasetuspto-grants-2013_05
ORD IDord-627b580c31f84f6dabb14a181ca24166
Source noteuspto-grants-2013_05