Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2092372Generated: October 31, 2026

(3,4-Difluorophenyl)(phenyl)methanol → Carbonic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)ester (3,4-difluoro-phenyl)-phenyl-methyl ester

https://huagongshe.com/reaction/2092372

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3,4-Difluorophenyl)(phenyl)methanolHCID 2758251—
Reactantimidazole-1-carboxylic acid (R)-1-aza-bicyclo[2.2.2]oct-3-yl esterHCID 59187189—
ProductCarbonic acid (R)-(1-aza-bicyclo[2.2.2]oct-3-yl)ester (3,4-difluoro-phenyl)-phenyl-methyl esterHCID 86638976—

Reaction Steps

The desired product was prepared by reacting imidazole-1-carboxylic acid (R)-1-aza-bicyclo[2.2.2]oct-3-yl ester with (3,4-difluoro-phenyl)-phenyl-methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08440690B2
Source datasetuspto-grants-2013_05
ORD IDord-48e489f708934b72a162e41151d7051d
Source noteuspto-grants-2013_05