HRID2092644
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
CONDITIONS
反应条件
- 温度
- 70 °C
PROCEDURE
实验过程
A mixture of ketone 10A (240 mg, 0.8 mmol) and Lawesson reagent (200 mg, 0.48 mmol) in anhydrous toluene was heated at 70° C. for overnight. The solvent was removed under vacuum and the residue was purified by silica gel chromatography [Hexane:EtOAc 4:1(v/v)] to give the title compounds 10B (130 mg, 54%). LC-MS (ESR): m/z=316 (M+H)+.
WORKUP
后处理
- customThe solvent was removed under vacuum
- customthe residue was purified by silica gel chromatography [Hexane:EtOAc 4:1(v/v)]