HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2092644Generated: October 31, 2026
Lawesson's reagent → HCID 58192775, compound
https://huagongshe.com/reaction/2092644
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Lawesson's reagent | HCID 87949 | — |
| Reactant | (4-Oxo-adamantan-1-yl)-carbamic acid benzyl ester | HCID 58192798 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 58192775 | HCID 58192775 | 85.9% |
Reaction Steps
A mixture of ketone 10A (240 mg, 0.8 mmol) and Lawesson reagent (200 mg, 0.48 mmol) in anhydrous toluene was heated at 70° C. for overnight. The solvent was removed under vacuum and the residue was purified by silica gel chromatography [Hexane:EtOAc 4:1(v/v)] to give the title compounds 10B (130 mg, 54%). LC-MS (ESR): m/z=316 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08440720B2 |
|---|
| Source dataset | uspto-grants-2013_05 |
|---|
| ORD ID | ord-5d6659d154ad43ba97be5949c6d51e76 |
|---|
| Source note | uspto-grants-2013_05 |
|---|
