Hydrochloric Acid → Hydrochloric Acid

Participants

Reaction Steps

A solution of oxime 14A (0.17 mmol) in 1,4-dioxane (2.0 mL) was diluted with a solution of 4 N HCl in dioxane (1.0 mL) and the reaction mixture was maintained at rt for 16 h. The reaction mixture was concentrated and dried to provide amine 14 in 88% yield as a hydrochloric acid salt. Data: LC/MS (ESR) m/z=195 [M+H]+.

Provenance & Evidence