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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2092681Generated: November 2, 2026

p-Fluoronitrobenzene → 4-((S)-2,2,2-Trifluoro-1-methyl-ethoxy)-phenylamine

https://huagongshe.com/reaction/2092681

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-FluoronitrobenzeneHCID 9590—
Reactant(2S)-1,1,1-Trifluoropropan-2-olHCID 6999971—
Product4-((S)-2,2,2-Trifluoro-1-methyl-ethoxy)-phenylamineHCID 66579896—

Reaction Steps

This material was made in analogy to example 142, step 1 from (S)-1,1,1-trifluoro-2-propanol [CAS 17628-73-8] and 1-fluoro-4-nitro-benzene [CAS 350-46-9]. MS (m/e): 206.1 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08440710B2
Source datasetuspto-grants-2013_05
ORD IDord-96d594fab5cb44d59964c6a8438523c2
Source noteuspto-grants-2013_05