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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2092685Generated: October 31, 2026

4-Ethylphenethylamine → 2-[2-(4-Ethyl-phenyl)-ethyl]-8-hydroxy-2-aza-spiro[4.5]decan-1-one

https://huagongshe.com/reaction/2092685

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-EthylphenethylamineHCID 144047—
Reactant4-Hydroxy-1-(2-methoxy-ethyl)-cyclohexanecarboxylic acid ethyl esterHCID 58229976—
Product2-[2-(4-Ethyl-phenyl)-ethyl]-8-hydroxy-2-aza-spiro[4.5]decan-1-oneHCID 52911978—

Reaction Steps

The title compound was prepared in analogy to example 1, step 4 from 4-hydroxy-1-(2-methoxy-ethyl)-cyclohexanecarboxylic acid ethyl ester (obtained in example 2, step 3) by treatment with 2-(4-ethylphenyl)-ethylamine [CAS Reg. No. 64353-29-3]. MS (m/e): 302.3 [MH+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08440710B2
Source datasetuspto-grants-2013_05
ORD IDord-dc6511f38bb143fe894678b4f730d6b3
Source noteuspto-grants-2013_05