Phenol, 4-amino-, 1-methanesulfonate → HCID 58230095, compound

HRID 2092692Notes

Reaction equation

HRID 2092692 reaction equation
C(O[C:4]([C:6]1([CH2:13][CH2:14]OC)[CH2:11][CH2:10][CH:9]([OH:12])[CH2:8][CH2:7]1)=[O:5])C.[NH2:17][C:18]1[CH:23]=[CH:22][C:21]([O:24][S:25]([CH3:28])(=[O:27])=[O:26])=[CH:20][CH:19]=1>>[OH:12][CH:9]1[CH2:8][CH2:7][C:6]2([C:4](=[O:5])[N:17]([C:18]3[CH:23]=[CH:22][C:21]([O:24][S:25]([CH3:28])(=[O:27])=[O:26])=[CH:20][CH:19]=3)[CH2:14][CH2:13]2)[CH2:11][CH2:10]1

Participants

3

Reactant 2

HCID 19885019Phenol, 4-amino-, 1-methanesulfonateHCID 582299764-Hydroxy-1-(2-methoxy-ethyl)-cyclohexanecarboxylic acid ethyl ester

Product 1

HCID 58230095HCID 58230095, compound

Procedure

The title compound was prepared in analogy to example 108, step 3 from 4-hydroxy-1-(2-methoxy-ethyl)-cyclohexanecarboxylic acid ethyl ester (obtained in example 2, step 3) by treatment with methanesulfonic acid 4-amino-phenyl ester (synthesis: S. Kobayashi, et al.; Synlett. 2000, p 883) as a mixture of cis and trans diastereomers. MS (m/e): 340.121 [MH+].

Sources & evidence

ORD record
ord-0b3af366129341d1bef91d32a180427f
Source dataset
uspto-grants-2013_05
Patent number
US08440710B2

Reaction notes

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