HuagongsheHuagongshe Chemistry Print Report · For research reference only
P-Anisidine → [(4-methoxyphenyl)amino]carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | P-Anisidine | HCID 7732 | — |
| Reactant | Cyanogen Bromide | HCID 10476 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | [(4-methoxyphenyl)amino]carbonitrile | HCID 10931588 | — |
Reaction Steps
To a solution of cyanobromide (0.6 eq) in diethyl ether, a solution of 4-methoxy phenyl amine (1.0 eq) in diethyl ether was added and the reaction mixture was stirred at room temperature for 2 h. Salt separated out was filtered and the filtrate was concentrated to afford the desired 4-methoxy-phenyl-cyanamide in good yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08440830B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-eea254c454994d64aea3c0a4af727066 |
| Source note | uspto-grants-2013_05 |