Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2093059Generated: November 3, 2026

P-Anisidine → [(4-methoxyphenyl)amino]carbonitrile

https://huagongshe.com/reaction/2093059

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
ReactantCyanogen BromideHCID 10476—
SolventDiethyl EtherHCID 3283—
Product[(4-methoxyphenyl)amino]carbonitrileHCID 10931588—

Reaction Steps

To a solution of cyanobromide (0.6 eq) in diethyl ether, a solution of 4-methoxy phenyl amine (1.0 eq) in diethyl ether was added and the reaction mixture was stirred at room temperature for 2 h. Salt separated out was filtered and the filtrate was concentrated to afford the desired 4-methoxy-phenyl-cyanamide in good yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08440830B2
Source datasetuspto-grants-2013_05
ORD IDord-eea254c454994d64aea3c0a4af727066
Source noteuspto-grants-2013_05