Dichloromethane → 3-[5-(2-Fluoro-phenyl)-pyridin-2-yloxy]-azetidine-1-carboxylic acid 4-nitro-phenyl ester

HRID 209309Notes

Reaction equation

HRID 209309 reaction equation
[CH:14]([c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)([c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1)[N:27]1[CH2:28][CH:29]([O:31][c:32]2[n:33][cH:34][c:35](-[c:38]3[c:39]([F:44])[cH:40][cH:41][cH:42][cH:43]3)[cH:36][cH:37]2)[CH2:30]1.[Cl:1][C:2](=[O:3])[O:4][c:5]1[cH:6][cH:7][c:8]([N+:11](=[O:12])[O-:13])[cH:9][cH:10]1.[Cl:45][CH2:46][Cl:47]>>[C:2](=[O:3])([O:4][c:5]1[cH:6][cH:7][c:8]([N+:11](=[O:12])[O-:13])[cH:9][cH:10]1)[N:27]1[CH2:28][CH:29]([O:31][c:32]2[n:33][cH:34][c:35](-[c:38]3[c:39]([F:44])[cH:40][cH:41][cH:42][cH:43]3)[cH:36][cH:37]2)[CH2:30]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 821294-Nitrophenyl chloroformateHCID 580730992-(1-Benzhydryl-azetidin-3-yloxy)-5-(2-fluoro-phenyl)-pyridine

Product 1

HCID 580731093-[5-(2-Fluoro-phenyl)-pyridin-2-yloxy]-azetidine-1-carboxylic acid 4-nitro-phenyl ester

Sources & evidence

ORD record
ord-a7011a54f14b46ec979c7def9ea64620
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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