Hydrochloric Acid → HCID 5702423, compound

Participants

Reaction Steps

To a solution of nitromethane (1.15 eq.) in ethanol (30 ml per gm of aldehyde) cooled to 0° C. was added dropwise a solution of 10N NaOH and stirred for 15 min. 3-thiopene carbaldehyde was added slowly under slitting at 0° C. and resulting reaction mixture was stirred for 1 hr. Reaction mixture was then poured on 10% icecold HCl solution and yellow solid was filtered and dried to yield the desired 3-[(E)-2-nitrovinyl]thiophene.

Provenance & Evidence