HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Hydroxide → (Benzo[1,3]dioxol-5-ylamino)-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | Ethyl 2-(1,3-benzodioxol-5-ylamino)acetate | HCID 745625 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (Benzo[1,3]dioxol-5-ylamino)-acetic acid | HCID 5229860 | — |
Reaction Steps
To a solution of compound (Benzo[1,3]dioxol-5-ylamino)-acetic acid ethyl ester in methanol was added lithium hydroxide (1.2 eq.) and stirred for overnight. Reaction mixture was then concentrated and neutralized to afford (Benzo[1,3]dioxol-5-ylamino)-acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08440830B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-f9055fe229f94d2cb1be45b8718fc4a9 |
| Source note | uspto-grants-2013_05 |