Ethanol → [4-(3,5-Difluorophenyl)-8-(Trifluoromethyl)Quinolin-3-yl](Phenyl)Methanone
Reaction equation
[CH3:41][CH2:42][OH:43].[CH3:45][O:46][CH2:47][CH2:48][O:49][CH3:50].[Cl:1][c:2]1[c:3]([C:16](=[O:17])[c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[cH:4][n:5][c:6]2[c:7]([C:12]([F:13])([F:14])[F:15])[cH:8][cH:9][cH:10][c:11]12.[F:24][c:25]1[cH:26][c:27]([B:32]([OH:33])[OH:34])[cH:28][c:29]([F:31])[cH:30]1.[Na+:35].[Na+:36].[O-:37][C:38](=[O:39])[O-:40].[OH2:44].[Pd:51].[c:109]1([P:110]([c:111]2[cH:112][cH:113][cH:114][cH:115][cH:116]2)[c:117]2[cH:118][cH:119][cH:120][cH:121][cH:122]2)[cH:123][cH:124][cH:125][cH:126][cH:127]1.[c:52]1([P:53]([c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[cH:66][cH:67][cH:68][cH:69][cH:70]1.[c:71]1([P:72]([c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)[c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)[cH:85][cH:86][cH:87][cH:88][cH:89]1.[c:90]1([P:91]([c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)[c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)[cH:104][cH:105][cH:106][cH:107][cH:108]1>>[c:2]1(-[c:27]2[cH:26][c:25]([F:24])[cH:30][c:29]([F:31])[cH:28]2)[c:3]([C:16](=[O:17])[c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[cH:4][n:5][c:6]2[c:7]([C:12]([F:13])([F:14])[F:15])[cH:8][cH:9][cH:10][c:11]12Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-ecce6ee913464e589bae2014ec66921c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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