4'-Hydroxyacetophenone → 6-(4-hydroxyphenyl)pyridazin-3(2H)-one

HRID 2093344Notes

Reaction equation

HRID 2093344 reaction equation
[CH3:1][C:2]([C:4]1[CH:5]=[CH:6][C:7]([OH:10])=[CH:8][CH:9]=1)=O.[N:11]1[NH:12][C:13](=[O:17])[CH:14]=CC=1>>[OH:10][C:7]1[CH:6]=[CH:5][C:4]([C:2]2[CH:1]=[CH:14][C:13](=[O:17])[NH:12][N:11]=2)=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 74694'-HydroxyacetophenoneHCID 681533(2H)-Pyridazinone

Product 1

HCID 1355906296-(4-hydroxyphenyl)pyridazin-3(2H)-one

Procedure

50 g of 4-hydroxyacetophenone are converted into the pyridazinone in accordance with GWP 1.

Sources & evidence

ORD record
ord-7d83d09362f84a1095b5d16abaf91ba1
Source dataset
uspto-grants-2013_05
Patent number
US08445489B2

Reaction notes

Loading…