3-Hydroxyacetophenone → 6-(3-Hydroxyphenyl)pyridazin-3(2H)-one

HRID 2093345Notes

Reaction equation

[CH3:1][C:2]([C:4]1[CH:5]=[CH:6][CH:7]=[C:8]([OH:10])[CH:9]=1)=O.[N:11]1[NH:12][C:13](=[O:17])[CH:14]=CC=1>>[OH:10][C:8]1[CH:9]=[C:4]([C:2]2[CH:1]=[CH:14][C:13](=[O:17])[NH:12][N:11]=2)[CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 84873-Hydroxyacetophenone

HCID 681533(2H)-Pyridazinone

Product 1

HCID 198846786-(3-Hydroxyphenyl)pyridazin-3(2H)-one

Procedure

15 g of 3-hydroxyacetophenone are converted into the pyridazinone in accordance with GWP 1.

Sources & evidence

ORD record: ord-d69d4cd3b18f42aabdb3715938563d14
Source dataset: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08445489B2

Reaction notes

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