Acetone → HCID 178429849, compound

HRID 2093354Notes

Reaction equation

HRID 2093354 reaction equation
[NH2:1][C:2]1[C:15]2[C:14](=[O:16])[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[C:7](=[O:17])[C:6]=2[CH:5]=[CH:4][C:3]=1[NH2:18].S(=O)(=O)(O)O.C(=O)([O-])[O-].[K+].[K+].[CH3:30][C:31]([CH3:33])=O>>[CH3:30][C:31]1([CH3:33])[NH:1][C:2]2[C:15]3[C:14](=[O:16])[C:13]4[C:8]([C:7](=[O:17])[C:6]=3[CH:5]=[CH:4][C:3]=2[NH:18]1)=[CH:9][CH:10]=[CH:11][CH:12]=4

Participants

5

Reactant 4

HCID 180AcetoneHCID 1118Sulfuric AcidHCID 11430Potassium CarbonateHCID 156521,2-Diaminoanthraquinone

Product 1

HCID 178429849HCID 178429849, compound

Procedure

1,2-Diaminoanthraquinone (1.19 g, 5 mmol) is dissolved in dry acetone (100 mL), and concentrated sulfuric acid (0.1 mL) is further added thereinto. After mixing and reacting in room temperature for 48 hours, the reacted mixture is transferred into a potassium carbonate column. The product is collected and recrystallized by methanol, so as to obtain the purple compound 20, and the production rate is 31%. In the purification steps of the Embodiment 21, regular extraction method will reduce the production rate, and thus the basic column is used to remove the acid in the rough extract, so as to increase the production rate.

Workup

  1. additionAfter mixing
  2. customThe product is collected
  3. customrecrystallized by methanol

Sources & evidence

ORD record
ord-f8802ee4af1c4905a5c6154d14b4e6da
Source dataset
uspto-grants-2013_05
Patent number
US08445492B2

Reaction notes

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