HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 1'-(5-methylpyrazin-2-yl)-4,4'-bipiperidine-1-carboxylate → 1-(5-Methylpyrazin-2-yl)-4,4'-bipiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 1'-(5-methylpyrazin-2-yl)-4,4'-bipiperidine-1-carboxylate | HCID 59178865 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 1-(5-Methylpyrazin-2-yl)-4,4'-bipiperidine | HCID 59178897 | — |
Reaction Steps
The tert-butyl 1′-(5-methylpyrazin-2-yl)-4,4′-bipiperidine-1-carboxylate (1 g, 2.8 mmol) was dissolved in trifluoroacetic acid and stirred at r.t. for 5 minutes. The solution was concentrated in vac. The residue was dissolved in toluene (10 mL) and concentrated in vac.(×2) to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445499B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-3a168a2289824881a11ed7126910e5c9 |
| Source note | uspto-grants-2013_05 |