反应详情

The tert-butyl 1′-(5-methylpyrazin-2-yl)-4,4′-bipiperidine-1-carboxylate (1 g, 2.8 mmol) was dissolved in trifluoroacetic acid and stirred at r.t. for 5 minutes. The solution was concentrated in vac. The residue was dissolved in toluene (10 mL) and concentrated in vac.(×2) to yield the title compound.

1. concentrationThe solution was concentrated in vac
2. dissolutionThe residue was dissolved in toluene (10 mL)
3. concentrationconcentrated in vac.(×2)