HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromobenzyl bromide → 1-Bromo-4-((methylsulfonyl)methyl)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromobenzyl bromide | HCID 68527 | — |
| Reactant | HCID 178504973 | HCID 178504973 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-Bromo-4-((methylsulfonyl)methyl)benzene | HCID 2761415 | — |
Reaction Steps
p-Bromobenzyl bromide (500 mg, 2 mmol) was refluxed with MeSO2Na (306 mg, 3 mmol) in Ethanol for 1 hour. The reaction was cooled, concentrated and purified by flash column (50% acetone/hexanes) to give the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445499B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-eda08050a15f4ecd80044bec3b2dae57 |
| Source note | uspto-grants-2013_05 |