Dichloromethane → 2-[4-Phenyl-1-(3-phenyl-propyl)-butylcarbamoyl]-piperidine

HRID 209349Notes

Reaction equation

HRID 209349 reaction equation
[CH2:43]([Cl:44])[Cl:45].[OH:36][C:37]([C:38]([F:39])([F:40])[F:41])=[O:42].[c:1]1([CH2:7][CH2:8][CH2:9][CH:10]([CH2:11][CH2:12][CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[NH:20][C:21](=[O:22])[CH:23]2[N:24]([C:29]([O:30][C:31]([CH3:32])([CH3:33])[CH3:34])=[O:35])[CH2:25][CH2:26][CH2:27][CH2:28]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH2:7][CH2:8][CH2:9][CH:10]([CH2:11][CH2:12][CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[NH:20][C:21](=[O:22])[CH:23]2[NH:24][CH2:25][CH2:26][CH2:27][CH2:28]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 121367652-[4-Phenyl-1-(3-phenyl-propyl)-butylcarbamoyl]piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 129924602-[4-Phenyl-1-(3-phenyl-propyl)-butylcarbamoyl]-piperidine

Sources & evidence

ORD record
ord-d90845126f504eda8d755e511a4412b0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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