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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2093650Generated: October 31, 2026

Water → HCID 68726219, compound

https://huagongshe.com/reaction/2093650

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantCyanuric chlorideHCID 7954—
ReactantHCID 68724707HCID 68724707—
SolventDimethylformamideHCID 6228—
ProductHCID 68726219HCID 68726219—

Reaction Steps

To a solution of 4-hydroxy-3-(trifluoromethoxy)benzamide (532 mg, 2.41 mmol) in dimethylformamide (3 ml) was added cyanuric chloride (223 mg, 1.21 mmol). The mixture was stirred for 25 and then water was added and the resulting solution was extracted 3 times with ethyl acetate. The combined organics were washed with brine, dried over sodium sulfate, and concentrated in vacuo to afford the title compound. Mass spectrum (ESI) 202.1 (M−1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445480B2
Source datasetuspto-grants-2013_05
ORD IDord-aec3fb1e187749468b29b12beaa4a742
Source noteuspto-grants-2013_05