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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2093652Generated: October 31, 2026

tert-Butyl 2,8-diazaspiro(4.5)decane-8-carboxylate → tert-Butyl-2-[4-(5-cyano-7-isopropyl-1,3-benzoxazol-2-yl)benzoyl]-2,8-diazaspiro[4.5]decane-8-carboxylate

https://huagongshe.com/reaction/2093652

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl 2,8-diazaspiro(4.5)decane-8-carboxylateHCID 23282900—
Reactant4-(5-Cyano-7-isopropylbenzo[d]oxazol-2-yl)benzoic acidHCID 57369945—
Producttert-Butyl-2-[4-(5-cyano-7-isopropyl-1,3-benzoxazol-2-yl)benzoyl]-2,8-diazaspiro[4.5]decane-8-carboxylateHCID 68745807—

Reaction Steps

The title compound was synthesized from 4-(5-cyano-7-isopropyl-1,3-benzoxazol-2-yl)benzoic acid (INTERMEDIATE 2) and tert-butyl 2,8-diazaspiro[4.5]decane-8-carboxylate following the procedure described in EXAMPLE 120. Mass spectrum (ESI) 529.2 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445480B2
Source datasetuspto-grants-2013_05
ORD IDord-b79e44af0a6e49d0902f8cb5699cd945
Source noteuspto-grants-2013_05