HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-Methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(cyclopentyl)amino)butanoate → (R)-methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(isopropyl)amino)butanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-Methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(cyclopentyl)amino)butanoate | HCID 58405447 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | (R)-methyl 2-((2-chloro-5-nitropyrimidin-4-yl)(isopropyl)amino)butanoate | HCID 59815009 | — |
Reaction Steps
Intermediate C-1 was prepared similarly to the synthetic methods used to prepare Intermediate A with the exception that acetone was used instead of cyclopentanone in the reductive amination step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08445503B2 |
| Source dataset | uspto-grants-2013_05 |
| ORD ID | ord-70504879d261429a8348f1526e580ab1 |
| Source note | uspto-grants-2013_05 |