1,1-Dimethoxyethyl(dimethyl)amine → HCID 67170049, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 1-(2,5-dimethyl-4-nitrophenyl)ethanone (Step 1, 300 mg, 1.55 mmol) and 1,1-dimethoxy-N,N-dimethylethanamine (1 mL) was heated in a microwave at 130° C. for 10 min. The crude product was purified with silica gel chromatography (60% ethyl acetate in hexanes) to afford 1-(2,5-dimethyl-4-nitrophenyl)-3-(dimethylamino)but-2-en-1-one as a yellow solid.

Provenance & Evidence