Bromomethylcyclopropane → 1-Bromo-2-(cyclopropylmethoxy)-4-fluorobenzene

HRID 2093839Notes

Reaction equation

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([F:8])=[CH:4][C:3]=1[OH:9].Br[CH2:11][CH:12]1[CH2:14][CH2:13]1>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([F:8])=[CH:4][C:3]=1[O:9][CH2:11][CH:12]1[CH2:14][CH2:13]1

Participants

Reactant 2

HCID 81503Bromomethylcyclopropane

HCID 27246002-Bromo-5-fluorophenol

Product 1

HCID 668669451-Bromo-2-(cyclopropylmethoxy)-4-fluorobenzene

Procedure

Starting from commercially available 2-bromo-5-fluoro-phenol and bromomethyl-cyclopropane the title compound is prepared as colorless oil

Sources & evidence

ORD record: ord-435cc005eecc4c3ca8c4cd87317a7dee
Source dataset: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08445501B2

Reaction notes

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