Bromomethylcyclopropane → 4-Fluoro-2-bromophenol methylcyclopropyl ether
Reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[OH:9].Br[CH2:11][CH:12]1[CH2:14][CH2:13]1>>[Br:1][C:2]1[CH:7]=[C:6]([F:8])[CH:5]=[CH:4][C:3]=1[O:9][CH2:11][CH:12]1[CH2:14][CH2:13]1Participants
3
Procedure
Starting from commercially available 2-bromo-4-fluoro-phenol and bromomethyl-cyclopropane the title compound is obtained as colorless oil.
Sources & evidence
- ORD record
- ord-1d7972cf839e4df585a0cf354ee80c4f
- Source dataset
- uspto-grants-2013_05
- Patent number
- US08445501B2
Reaction notes
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