Lithium Hydroxide → 3-Methoxy-4-(piperidin-2-on-1-yl)benzoic acid

HRID 2094280Notes

Reaction equation

HRID 2094280 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][C:12]=1[N:13]1[CH2:18][CH2:17][CH2:16][CH2:15][C:14]1=[O:19])[C:6]([O:8]C)=[O:7].[OH-].[Li+]>C(O)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[CH:11][C:12]=1[N:13]1[CH2:18][CH2:17][CH2:16][CH2:15][C:14]1=[O:19])[C:6]([OH:8])=[O:7]

Participants

4

Reactant 2

HCID 3939Lithium HydroxideHCID 53419638HCID 53419638, compound

Product 1

HCID 670493433-Methoxy-4-(piperidin-2-on-1-yl)benzoic acid

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Prepared analogously to Example 39d from methyl 3-methoxy-4-(piperidin-2-on-1-yl)-benzoate and lithium hydroxide in ethanol.

Sources & evidence

ORD record
ord-a37a115ebafc4713a6730b6eaebc91d9
Source dataset
uspto-grants-2013_05
Patent number
US08445525B2

Reaction notes

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