Dichloromethane → N-isopropyl-N-methyl-cis-cyclohexane-1,4-diamine

HRID 209429Notes

Reaction equation

HRID 209429 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]1[CH2:9][CH2:10][CH:11]([N:14]([CH3:15])[CH:16]([CH3:17])[CH3:18])[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:19].[Cl:27][CH2:28][Cl:29].[OH:20][C:21]([C:22]([F:23])([F:24])[F:25])=[O:26]>>[NH2:7][CH:8]1[CH2:9][CH2:10][CH:11]([N:14]([CH3:15])[CH:16]([CH3:17])[CH3:18])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 69285738[cis-4-(Isopropyl-methyl-amino)-cyclohexyl]-carbamic acid tert-butyl ester

Product 1

HCID 18419789N-isopropyl-N-methyl-cis-cyclohexane-1,4-diamine

Sources & evidence

ORD record
ord-98a9d09d93884096814f413b385f398f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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