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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2094296Generated: October 31, 2026

Water → 3-Chloro-4-(3,6-dihydro-[1,2]oxazin-2-yl)-benzoic acid

https://huagongshe.com/reaction/2094296

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantSodium HydroxideHCID 14798—
ReactantMethyl 3-chloro-4-(3,6-dihydro-[1,2]oxazin-2-yl)-benzoateHCID 67048463—
SolventEthanolHCID 702—
Product3-Chloro-4-(3,6-dihydro-[1,2]oxazin-2-yl)-benzoic acidHCID 67048520—

Reaction Steps

Prepared analogously to Example 2d from methyl 3-chloro-4-(3,6-dihydro-[1,2]oxazin-2-yl)-benzoate and sodium hydroxide in a solvent mixture of water and ethanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445525B2
Source datasetuspto-grants-2013_05
ORD IDord-2870d389c2bb4490a51c9d5e63212407
Source noteuspto-grants-2013_05