Potassium tertbutoxide → Methyl 4-(1,1-dioxo-[1,2]thiazepan-2-yl)-3-methyl-benzoate

HRID 2094302Notes

Reaction equation

HRID 2094302 reaction equation

Cl[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][S:7]([NH:10][C:11]1[CH:20]=[CH:19][C:14]([C:15]([O:17][CH3:18])=[O:16])=[CH:13][C:12]=1[CH3:21])(=[O:9])=[O:8].[K].CC(C)([O-])C>CN(C=O)C>[O:8]=[S:7]1(=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][N:10]1[C:11]1[CH:20]=[CH:19][C:14]([C:15]([O:17][CH3:18])=[O:16])=[CH:13][C:12]=1[CH3:21]

Participants

4

Reactant 2

HCID 50987170Potassium tertbutoxide

HCID 67048451HCID 67048451, compound

Product 1

HCID 67048761Methyl 4-(1,1-dioxo-[1,2]thiazepan-2-yl)-3-methyl-benzoate

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Prepared analogously to Example 83b from methyl 4-(5-chloropentyl-sulphonyl-amino)-3-methyl-benzoate and potassium-tert.-butoxide in DMF.

Sources & evidence

ORD record: ord-8563505c462347e6b851209eb9eca4f7
Source dataset: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08445525B2

Reaction notes

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