2-Nitro-4-propylphenol → 55296-63-4

HRID 2094436Notes

Reaction equation

HRID 2094436 reaction equation
[CH2:1]([C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[C:6]([N+:11]([O-])=O)[CH:5]=1)[CH2:2][CH3:3].[H][H]>[Pd].C(OCC)(=O)C>[NH2:11][C:6]1[CH:5]=[C:4]([CH2:1][CH2:2][CH3:3])[CH:9]=[CH:8][C:7]=1[OH:10]

Participants

5

Reactant 2

HCID 2405532-Nitro-4-propylphenolHCID 178418361HCID 178418361, compound

Product 1

HCID 72113855296-63-4Yield 93.2%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

A mixture of 6.65 g of 4-propyl-2-nitrophenol, 55 ml of ethyl acetate and 1.0 g of 5% palladium on carbon was stirred under about one atmosphere of hydrogen at room temperature for two hours. The mixture was filtered through Celite™. The filtrate was concentrated under reduced pressure to give 5.17 g of 2-amino-4-propylphenol.

Workup

  1. filtrationThe mixture was filtered through Celite™
  2. concentrationThe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-bf6eda5cb9b54ffcafd6fe0a290e348c
Source dataset
uspto-grants-2013_05
Patent number
US08445522B2

Reaction notes

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