4-Aminopyridine → Carbamic acid, 4-pyridinyl-, phenyl ester

HRID 2094615Notes

Reaction equation

[NH2:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1.Cl[C:9]([O:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:10]>>[N:5]1[CH:6]=[CH:7][C:2]([NH:1][C:9](=[O:10])[O:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:3][CH:4]=1

Participants

Reactant 2

HCID 17274-Aminopyridine

HCID 15891Phenyl chloroformate

Product 1

HCID 11401617Carbamic acid, 4-pyridinyl-, phenyl esterYield 534%

Procedure

The title compound was prepared by following the procedure of example 462 step 6 using 4-aminopyridine and phenyl chloroformate. Yield 6 g, 534% yield.

Sources & evidence

ORD record: ord-4c899d490cd347eaa92f86bff121f757
Source dataset: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08445486B2

Reaction notes

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