Lithium Hydroxide → HCID 67076764, compound

HRID 2094680Notes

Reaction equation

C([O:3][C:4]([C:6]1([NH:15][C:16](=[O:35])[C:17]2[CH:22]=[CH:21][C:20]([O:23][CH3:24])=[C:19]([O:25][CH2:26][CH2:27][C:28]3[CH:29]=[C:30]([CH3:34])[CH:31]=[CH:32][CH:33]=3)[CH:18]=2)[CH2:14][C:13]2[N:12]=[CH:11][CH:10]=[CH:9][C:8]=2[CH2:7]1)=[O:5])C.[OH-].[Li+]>>[CH3:24][O:23][C:20]1[CH:21]=[CH:22][C:17]([C:16]([NH:15][C:6]2([C:4]([OH:5])=[O:3])[CH2:14][C:13]3[N:12]=[CH:11][CH:10]=[CH:9][C:8]=3[CH2:7]2)=[O:35])=[CH:18][C:19]=1[O:25][CH2:26][CH2:27][C:28]1[CH:29]=[C:30]([CH3:34])[CH:31]=[CH:32][CH:33]=1

Participants

Reactant 2

HCID 3939Lithium Hydroxide

HCID 67239232HCID 67239232, compound

Product 1

HCID 67076764HCID 67076764, compound

Procedure

The compound of step 1 was hydrolyzed with lithium hydroxide in analogy to step 3 of example 94 to give 5 mg of the title compound.

Sources & evidence

ORD record: ord-698053a2aa5f4260ba42063b22ba6ed5
Source dataset: uspto-grants-2013_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08445530B2

Reaction notes

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