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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2094840Generated: October 30, 2026

Pyrimidin-5-ylmethanamine → HCID 178518107, compound

https://huagongshe.com/reaction/2094840

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrimidin-5-ylmethanamineHCID 18953632—
Reactant5-[1-(2,4-bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]2-methylsulfanyl-thiazol-4-oneHCID 86654543—
ProductHCID 178518107HCID 178518107—

Reaction Steps

5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-[(pyrimidin-5-ylmethyl)-amino]-thiazol-4-one was prepared from 5-[1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-methylsulfanyl-thiazol-4-one and C-pyrimidin-5-yl-methylamine following General Procedure B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08445690B2
Source datasetuspto-grants-2013_05
ORD IDord-22ef90134462433bb7114cabcecef9cf
Source noteuspto-grants-2013_05